and it did take many months before I felt real benefits from the injections
Safety, Tolerability & Regulatory Status Safety Profile GHK-Cu demonstrates an excellent safety profile for cosmetic use: Naturally occurring in humans (plasma, saliva, urine) Non-sensitizing in standard patch testing at cosmetic concentrations Long history of topical application in anti-aging and wound care products Minimal reported adverse reactions at appropriate doses Usage Levels and Tolerability Regulatory Status EU : Permitted as a cosmetic ingredient with standard safety assessments US/Asia-Pacific : Allowed under respective cosmetic regulations Formulators must : Perform product-specific safety evaluations, including SDS review, toxicological profiles, and margin of safety calculations Addressing Copper Uglies Literature occasionally references theoretical over-stimulation of MMPs leading to collagen breakdown (sometimes called copper uglies)
Gastrointestinal side effects, particularly nausea and vomiting, may further compromise nutritional status by limiting food intake
10.1016/j.neuroscience.2007.09.074 397
GHK is a naturally occurring peptide, while GHK-Cu is the peptide bound to copper, which activates its biological signaling functions
